I am in a legal embroilment and my lawyer put the defendant under surveillance to assess the case.  The surveillance came with a DNA report.  This is a newer legal service in Canada, where any evidence can be obtained and is fair game.

http://www.macleans.ca/news/canada/new-evidence-in-diefenbaby-case/

The following genetic defects were reported:

Rs429358 – 

One meta-analysis estimated the odds ratios for homozygous rs429358(C;C) individuals compared to the more common ApoE3/ApoE3 homozygotes to be 12x for late-onset Alzheimer’s and 61x for early-onset disease.

APOE-e4 –

Apolipoprotein E-e4 (APOE4), discovered in 1993, is the first gene variation found to increase risk of Alzheimer’s and remains the risk gene with the greatest known impact. Having this mutation, however, does not mean that a person will develop the disease.

Presenilin-1 (PS-1) –

Presenilin-1 (PS-1), identified in 1992, is the second gene with mutations found to cause inherited Alzheimer’s. Variations in this gene are the most common cause of inherited Alzheimer’s.

rs1333049 –

rs1333049 has been reported in a large study to be associated with heart disease, in particular, coronary artery disease.

This SNP has also been reported to have the highest association of any SNP studied in a subsequent experiment conducted with the resources of the German MI [Myocardial Infarction] Family Study.

(All quotes can be found at: http://www.snpedia.com/index.php/SNPedia)

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